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Host cell Z-RNAs activate ZBP1 during virus infections

Yin C, Fedorov A, Guo H, Crawford JC, Rousseau C, Zhong X, Williams RM, Gautam A, Koehler HS, Whisnant AW, Hennig T, Rozina A, Zhong Y, Lv S, Bergant V, Wang S, Dröge P, Miller S, Poptsova M, Rehwinkel J, Pichlmair A, Mocarski ES, Thomas PG, Dölken L, Zhang T, Herbert A, Balachandran S

Z-DNAimmunity

Nature, 2025 doi:10.1038/s41586-025-09705-5

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